KMID : 0363220080460091236
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Korean Journal of Dermatology 2008 Volume.46 No. 9 p.1236 ~ p.1239
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Two Cases of Hand-Foot Syndrome Induced by Sunitinib
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Jeong Jin-Seob
Yun Jeong-Hyun Yun Seok-Joong Kim Wun-Jae Lee Ji-Yeoun Yoon Tae-Young
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Abstract
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Sunitinib (SU11248) is a novel orally administered small molecule that inhibits multiple receptor tyrosine kinases so that can block tumor growth and angiogenesis. It was approved on 2006, for the treatment of advanced renal cell carcinoma and gastrointestinal stromal tumor. Various cutaneous adverse reactions induced by sunitinib have been reported, including hand-foot syndrome. We report two cases of hand-foot syndrome induced by sunitinib for treatment of advanced renal cell carcinoma.
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KEYWORD
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Hand-foot syndrome, Sunitinib, Tyrosine kinase inhibitor
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